RNA Structure

Local RNA Target Structure Influences siRNA Efficacy: A Systematic Global Analysis

Thermodynamics / Molecular Biology / Computational Biology / Gene Silencing / Global Analysis / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus

Local RNA Target Structure Influences siRNA Efficacy: A Systematic Global Analysis

Thermodynamics / Molecular Biology / Computational Biology / Gene Silencing / Global Analysis / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus / Genetic Engineering / Molecular / RNA interference / Cercopithecus aethiops / Cell line / Humans / RNAi / Animals / Drug Design / Free Energy / Rats / dsRNA / Substrate Specificity / Fluorescent Protein / Transfection / siRNA / RNA Structure / Base Sequence / TRP / UTR / GFP / Nucleic Acid Conformation / Biochemistry and cell biology / Enterovirus

Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency

Algorithms / Thermodynamics / RNA / Biotechnology / RNA silencing / Multidisciplinary / Gene Silencing / Nature / RNA interference / Cell line / Humans / Plasmids / microRNAs / Secondary Structure / Degeneration / RNA Structure / Structure Determination / RNA Secondary Structure / Nucleic Acid Conformation / Nucleotides / Multidisciplinary / Gene Silencing / Nature / RNA interference / Cell line / Humans / Plasmids / microRNAs / Secondary Structure / Degeneration / RNA Structure / Structure Determination / RNA Secondary Structure / Nucleic Acid Conformation / Nucleotides

Lock-free parallel dynamic programming

Distributed Computing / Constraint Programming / Parallel & Distributed Computing / Hash Table / Parallel / RNA Structure / Top Down / Shortest Path / RNA Structure / Top Down / Shortest Path

Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency

Algorithms / Thermodynamics / RNA / Biotechnology / RNA silencing / Multidisciplinary / Gene Silencing / Nature / RNA interference / Cell line / Humans / Plasmids / microRNAs / Secondary Structure / Degeneration / RNA Structure / Structure Determination / RNA Secondary Structure / Nucleic Acid Conformation / Nucleotides / Multidisciplinary / Gene Silencing / Nature / RNA interference / Cell line / Humans / Plasmids / microRNAs / Secondary Structure / Degeneration / RNA Structure / Structure Determination / RNA Secondary Structure / Nucleic Acid Conformation / Nucleotides

Conserved RNA secondary structures promote alternative splicing

Algorithms / RNA / Gene expression / Protein Structure and Function / Humans / Sequence alignment / Animals / Alternative splicing / Genome Analysis / Site Selection / Human Genome / Alternative Splicing / RNA Structure / Base Sequence / RNA Secondary Structure / Nucleic Acid Conformation / Biochemistry and cell biology / Sequence alignment / Animals / Alternative splicing / Genome Analysis / Site Selection / Human Genome / Alternative Splicing / RNA Structure / Base Sequence / RNA Secondary Structure / Nucleic Acid Conformation / Biochemistry and cell biology

Nucleotide sequences of trpA of Salmonella typhimurium and Escherichia coli: an evolutionary comparison

Multidisciplinary / Recombinant DNA Technology / Escherichia coli / Salmonella Typhimurium / Plasmids / Biological evolution / Genetic variation / Molecular weight / Codon / Species Specificity / RNA Structure / Amino Acid Sequence / Base Sequence / Biological evolution / Genetic variation / Molecular weight / Codon / Species Specificity / RNA Structure / Amino Acid Sequence / Base Sequence
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